Essential component of the citric acid cycle and source of calcium

Alpha-ketoglutarate is an endogenous substance produced from the amino acid glutamine and acts as an intermediate in the citric acid cycle, which takes place in the mitochondrial matrix. The citric acid cycle is a biochemical metabolic pathway that provides energy for all essential cell functions and plays a role in the breakdown of carbohydrates, fats, and proteins. Alpha-ketoglutarate is bound to calcium. Calcium is a vital mineral in the human body, with 99% of it present in bones and teeth as calcium phosphate compounds. Alpha-Ketoglutarat mse® contains pure calcium alpha-ketoglutarate. Among other things, calcium contributes to normal energy-yielding metabolism, normal muscle function, and normal neurotransmission between nerve cells.

Alpha-ketoglutarate is an endogenous substance that, as an intermediate, is involved in the smooth running of energy conversion into ATP – the "energy currency" of cells.